Artemisia capillaris – Yin Chen

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[Medicinal use] Seedlings of Artemisia scoparia Waldst.etkit. or Artemisia capillaris thumb, herbaceous plants of the Asteraceae family.
[Nature and flavor and meridians] Bitter, slightly cold. Enters the spleen, stomach, liver, and gallbladder meridians.
[Effects] Clears heat and dampness, relieves jaundice.
[Clinical application] Used for damp-heat jaundice
Artemisia scoparia is bitter and descending, and specializes in clearing dampness and heat. It is a key medicine for treating jaundice. It is mainly used for jaundice caused by damp-heat fumigation. It can be used alone, decocted in large doses, or taken orally; it can also be used in combination with rhubarb, gardenia, etc. If urination is significantly difficult, it can be used in combination with oriental rhizome, umbellate, etc. This product has a very good effect in relieving jaundice, so in addition to being used for damp-heat jaundice, it can also be used for Yin jaundice caused by cold and dampness or yang deficiency. However, it must be used together with warming and cold-dispelling herbs such as aconite and dried ginger to eliminate the cold and relieve jaundice.
[Prescription name] Artemisia capillaris, Artemisia capillaris, Artemisia capillaris, Artemisia capillaris (wash, dry, and chop)
[General dosage and usage] Three to one tael, decocted and taken orally.
[Attached medicine] Bell Artemisia capillaris: the whole herb of the herbaceous plant Yinxingcao of the Scrophulariaceae family. The function is similar to that of Artemisia capillaris, but in many northern regions, this product is used as “Liu Ji Nu”.
[Comments] 1. Artemisia capillaris is bitter and cold, clears heat and removes dampness, and is specialized in treating jaundice. It has a strong effect and can regulate the yin and yang of jaundice with the help of adjuvants. Therefore, it is commonly used in clinical practice. Although it is included in diuretics and has a slight effect of penetrating dampness, its effect of promoting urination is not significant. According to pharmacological research, this product has a beneficial effect on jaundice, can increase bile secretion, and has a fever-removing effect, which is enough to prove that the clinical experimental experience for thousands of years is indeed valuable.
2. The ancients believed that jaundice was caused by the accumulation of dampness and heat in the spleen and stomach, so they used it as a medicine for the spleen and stomach meridians; however, dampness and heat must fumigate the liver and gallbladder, causing the gallbladder to overflow and jaundice to appear, so modern people also believe that this product is related to the liver and gallbladder. This is the development of cognition and is consistent with reality, which should be recognized by the public.
3. Although Artemisia capillaris is an important medicine for jaundice, modern people also use it to treat acute non-icteric hepatitis. It can also be effective for all cases caused by dampness and heat, so it is not necessary to restrict it to jaundice.
[Examples of prescriptions] 1. Artemisia capillaris soup (Treatise on Febrile Diseases): Artemisia capillaris, gardenia, rhubarb. Treats typhoid fever for eight or nine days, with yellow body like orange color, difficulty urinating, and slightly full abdomen.
2. Artemisia capillaris Sini Tang (Yuji Weiyi): Artemisia capillaris, aconite, dried ginger, and moxibustion liquorice. Treats cold and damp yin jaundice, cold hands and feet, and deep and fine pulse.
3. Danyutong (Selected Technical Data from the National Exhibition of New Chinese Herbal Medicine Treatment Methods): Artemisia capillaris, Curcuma aromatica, Licorice root. Treats acute infectious hepatitis in children.
【Literature Excerpt】《Compendium of Materia Medica》: “Artemisia capillaris is used to treat rheumatism, cold and heat, evil qi and heat accumulation, jaundice, yellowing of the whole body, difficulty urinating and hot head, all of which are caused by dampness and heat in Yangming and Taiyin. Bitter and cold, it can dry out dampness and heat. Once dampness and heat are gone, all symptoms will naturally subside. It is an essential medicine for removing dampness and relieving heat.”
《Compendium of Materia Medica Gou Shu Yuan》: “It can dissipate the old and bring in the new, which is different from other herbs that can dispel dampness and heat, and it is even more difficult to match the effect of penetrating and benefiting.”
《Compendium of Materia Medica Illustrated》: “There are two types of jaundice, Yin and Yang. Artemisia capillaris is used with Gardenia jaundice and Phellodendron chinense to treat Yang jaundice, and with Aconite and dried ginger to treat Yin jaundice. In short, Artemisia capillaris is the main ingredient, and the auxiliary ingredients are used to treat cold and heat to regulate the Yin and Yang of jaundice.”
This product is the dried aerial part of Artemisia scoparia Waldst.et Kit, or Artemisia capilaris Thunb., a plant of the Asteraceae family. Harvest in spring when the seedlings are 6-10cm tall or harvest in autumn when the flower buds grow to the beginning of the flowers, remove impurities and old stems, and dry in the sun. Harvested in spring is commonly known as “cotton wormwood”, and harvested in autumn is called “flower wormwood”.
[Характеристики]
Wort wormwood is mostly curled into a ball, grayish white or grayish green, densely covered with white hairs, soft like velvet. The stem is small, 1.5-2.5cm long, 0.1-0.2cm in diameter, and obvious longitudinal lines can be seen after removing the white hairs on the surface; it is brittle and easy to break. The leaves are petiolate: when flattened, the leaves are pinnately divided one to three times, the leaves are 1-3cm long and about 1cm wide; the lobes are ovate or slightly oblanceolate, strip-shaped, with sharp tips. The smell is fresh and the taste is slightly bitter.
Artemisia capillaris The stem is cylindrical, branched, 30-100 cm long, 2-8 mm in diameter; the surface is lavender or purple, with longitudinal stripes and short soft hairs; the body is light, brittle, and white in cross section. The leaves are densely packed or mostly fall off; the lower leaves are deeply pinnate two to three times, with strip-shaped or thin strip-shaped lobes, densely covered with white soft hairs on both sides; the stem leaves are pinnate one to two times, clasping the stem at the base, with filamentous lobes. The head inflorescence is ovate, most of which are integrated into a cone, 1.2-1.5 mm long, 1-1.2 mm in diameter, with short stalks; the involucral bracts are 3-4 layers, ovate, and 3-lobed: the outer layer has 6-10 female flowers, up to 15, and the inner layer has 2-10 bisexual flowers. Achenes are oblong and yellow-brown. The smell is fragrant and the taste is slightly bitter.
【Identification】
(1) The powder of this product is gray-green. The non-glandular hairs are T-shaped, 600-1700 μm long, slightly folded into a V-shape in the middle, with arms of unequal length, extremely thick cell walls, slit-like cell cavities, and 1-2 fine cotton cells on the petiole. The periclidinal wall of the epidermal cells under the leaves is wavy, with irregular stomata and 3-5 accessory cells. The glandular hairs are relatively small, oval or shoe-shaped when viewed from the top, and the cells are stacked in pairs.
(2) Take 0.5 g of the powder of this product, add 50% methanol for 20 min, ultrasonically treat for 30 minutes, centrifuge, and take the supernatant as the test solution. Take another chlorogenic acid reference substance, add methanol to make a solution containing 0.1 mg per 1 ml as the reference solution. According to the thin layer chromatography method (general rule 0502), 2 μl of each of the above two solutions were taken and spotted on the same brick glue G thin layer plate, and the upper layer solution of butyl acetate-formic acid-water (7:2.5:2.5) was used as the developing agent. After development, the plate was taken out, dried, and examined under ultraviolet light (365nm). In the chromatogram of the test sample, the fluorescent spot of the same color appeared at the corresponding position of the chromatogram of the reference sample.
Artemisia capillaris Take 0.4g of the powder of this product, add 10ml of methanol, ultrasonically treat for 30 minutes, filter, recover the solvent in the filtrate until dry, add 2ml of methanol to the residue to dissolve it, and use it as the test solution. Take another artemisinin reference substance, add methanol to make a solution containing 0.4mg per 1ml, as the reference solution. According to the thin layer chromatography method (General Rule 0502), take 5 of the above two solutions, respectively, and spot them on the same tridacna G thin layer plate, use petroleum ether (60~90℃)-ethyl acetate-acetone (6:3:0.5) as the developing agent, develop, take out, dry, and examine under ultraviolet light (365nm). In the chromatogram of the test product, at the corresponding position of the chromatogram of the reference substance, a fluorescent spot of the same color appears.
[Inspection)
The water content shall not exceed 12.0% (General Rule 0832 Second Method).
【Extract】
According to the hot soaking method under the water-soluble extract determination method (General Rule 2201), the content shall not be less than 25.0%.
【Определение содержания】
According to the high performance liquid chromatography method (General Rule 0512).
Chromatographic conditions and system suitability test: Octadecylsilane bonded silica gel is used as filler; acetonitrile-0.05% phosphoric acid solution (10:90) is used as mobile phase; the detection wavelength is 327nm. The theoretical plate number calculated based on the chlorogenic acid peak should not be less than 5000.
Preparation of reference solution: Take an appropriate amount of chlorogenic acid reference substance, accurately weigh it, put it in a brown volumetric flask, and add 50% methanol to make a solution containing 40ug per 1ml. Preparation of test solution Take about 1g of the powder of this product (passed through No. 2 sieve), weigh accurately, place in a county-based conical flask, accurately add 50ml of 50% methanol, weigh the weight, ultrasonically treat (power 180W, frequency 42KH2) for 30 minutes, cool, weigh again, make up the lost weight with 50% methanol, shake well, centrifuge, accurately measure 5ml of supernatant, place in a 25ml brown volumetric flask, add 50% methanol to the scale, shake well, filter, and take the filtrate.
Determination method Accurately aspirate 10ml of reference solution and 5~20ml of test solution, inject into liquid chromatograph, and determine.
This product, calculated on the basis of dry product, contains no less than 0.50% chlorogenic acid (C16H18Og).
Artemisia capillaris Determine according to high performance liquid chromatography (General Rule 0512).
Chromatographic conditions and system suitability test Octadecyl tridane bonded tridacyl gum was used as filler: acetonitrile-water (20:80) was used as mobile phase: detection wavelength was 345nm, and the number of theoretical plates should be no less than 2000 according to the peak of artemisinin.
Preparation of reference solution Take an appropriate amount of artemisinin reference, accurately weigh it, add methanol to make a solution containing 20ug per 1ml, and obtain
Preparation of test solution Take about 0.2g of this product powder (passed through No. 2 sieve), accurately weigh it, put it in a stoppered conical bottle, accurately add 50ml of methanol, weigh it, heat and reflux for 40 minutes, cool it, weigh it again, make up the lost weight with methanol, shake it well, centrifuge it, and take the supernatant to obtain it.
Determination method Accurately aspirate 10ml of reference solution and test solution respectively, inject it into liquid chromatograph, and determine it.
This product contains no less than 0.20% of artemisinin (C11H1004) calculated on a dry basis.

Кусочки отвара

[Processing]
Remove the remaining roots and impurities, and crush or chop them. Sieve the ash from the Artemisia capillaris,

[Nature and flavor and meridians)
Anxin, slightly cold. It enters the spleen, stomach, liver, and gallbladder meridians,

[Функции и показания]
Clears dampness and heat, promotes bile secretion and reduces jaundice. Used for jaundice, oliguria, damp-heat, summer heat, and itching of wet sores

[Применение и дозировка]
6~15g. For external use, decoct in water and fumigate.

[Хранилище]
Place in a cool, dry place to prevent moisture.

Where is the main production area of ​​Artemisia capillaris?

It is mainly produced in Shaanxi, Shanxi, and Hebei.
Where is the main medicinal part of Artemisia scoparia?
Medicinal part of Artemisia scoparia:
Artemisia scoparia is the dry above-ground part of Artemisia scoparia Waldst.etKit. or Artemisia capillaris Thunb. of Asteraceae. It is harvested in spring when the seedlings are 6~10cm high or harvested in autumn when the buds grow to the beginning of the flowers. Impurities and old stems are removed and dried.
The ones harvested in spring are commonly called “cotton artemisia”, and those harvested in autumn are called “flower artemisia”. Characteristics of the medicinal part of Artemisia:
The cotton artemisia is mostly curled into a ball, grayish white or grayish green, and the whole body is densely covered with white hairs, soft like velvet. The stem is small, 1.5~2.5cm long, 0.1~0.2cm in diameter, and obvious longitudinal lines can be seen after removing the white hairs on the surface; it is brittle and easy to break.
The leaves are petiolate; when flattened, the leaves are pinnately divided one to three times, 1~3cm long and about 1cm wide; the lobes are ovate or slightly oblanceolate, with sharp tips at the tip. It has a fresh fragrance and a slightly bitter taste.
How are Artemisia capillaris recorded in ancient books?
“Shennong’s Herbal Classic”: “It is mainly used to treat wind, cold, dampness, heat and evil spirits, and jaundice caused by heat.
“Famous Doctors’ Records”: “It treats jaundice of the whole body, difficulty urinating, and heat in the head, and removes hidden scars.
“Compendium of Materia Medica”: “Artemisia capillaris, with a light taste and diuretic effect, is a special medicine for treating dampness and heat in the spleen and stomach.
Effects
Artemisia capillaris has the effects of clearing dampness and heat, promoting bile and relieving jaundice.
What are the main effects and clinical applications of Artemisia capillaris?
Artemisia capillaris is used for jaundice, oliguria, damp-heat and summer-heat dampness, and itching of wet sores.
Jaundice
It is often used with Gardenia and Rhubarb to treat Yang jaundice caused by damp-heat stagnation;
It is often used with Aconite and Dry Ginger to treat Yin jaundice caused by cold-dampness stagnation.
Itching of wet sores
It can be decocted as a single herb for external washing, or used with Phellodendron, Sophora flavescens, Kochia scoparia, etc.
What are the compound preparations containing Artemisia capillaris?
Yinshanlian Granules
It clears heat, detoxifies and removes dampness. It is used for flank pain, bitter mouth, yellow urine, yellow and greasy tongue coating, and stringy and slippery pulse caused by damp-heat toxicity; acute and chronic hepatitis, cholecystitis with the above symptoms.
Yinqi Ganfu Granules
It clears heat, detoxifies and removes dampness, soothes the liver and nourishes the spleen. Used for chronic hepatitis B, liver and gallbladder damp-heat and spleen deficiency and liver depression, with symptoms of right flank distension, nausea, aversion to oil, poor appetite, and bland taste in the mouth.
Yindan Pinggan Capsule
Clears heat, promotes dampness, and relieves jaundice. Used for flank pain, bitter mouth, yellow urine, and yellow eyes and body caused by liver and gallbladder damp-heat; acute and chronic hepatitis with the above symptoms.
Yinzhihuang Oral Liquid
Clears heat and detoxifies, promotes dampness and relieves jaundice. Used for jaundice caused by liver and gallbladder damp-heat, with symptoms of yellow face, chest and flank distension and pain, nausea and vomiting, and yellow and red urine; acute and chronic hepatitis with the above symptoms
Ganlu Xiaodu Dan
Promotes dampness and turbidity, clears heat and detoxifies. Indications: damp-heat epidemic, evil in the qi, dampness and heat syndrome,
Yinchen Wuling Powder
Promotes dampness and relieves jaundice. Indications: damp-heat jaundice, dampness is heavier than heat, and urination is difficult
Yinchen Sini Decoction
Warms the interior and assists yang, promotes dampness and relieves jaundice. Indications: Yin jaundice. Dark yellow, cold skin , back aversion to cold, hands and feet not warm, body heavy, tired and less food, no thirst or thirsty like hot drinks, loose stools.
Yinchenhao Decoction
Clears heat, promotes dampness, and reduces jaundice. Indications: damp-heat jaundice. The whole face is yellow, bright yellow, fever, no sweat or only sweating on the head, thirsty, nausea and vomiting, slightly full abdomen, short and red urine, uncomfortable or constipated stools.
Modern research progress on Yinchen
This product has multiple pharmacological effects such as anti-liver damage, bile-promoting, anti-pathogenic microorganisms, and anti-tumor.
Usage
Yinchen has the effects of clearing dampness and heat, promoting bile and reducing jaundice, and can be taken orally or externally. Please follow the doctor’s instructions for specific medication.
How to use Yinchen correctly?
When Yinchen decoction is taken orally, the usual dosage is 6~15g.
When used externally, take an appropriate amount of Yinchen decoction to fumigate the affected area, which has a therapeutic effect on wet sores and itching.
Generally, it is added to decoctions, and decoctions are used. It can be taken as juice, or made into powder or pills. However, the use of Chinese herbal medicines must be treated according to the syndrome differentiation and should be used under the guidance of professional Chinese medicine practitioners. It should not be used at will, and it is even more forbidden to listen to Chinese medicine prescriptions and advertisements at will.
How to prepare Artemisia capillaris?
Take the original medicinal materials, remove the residual roots, old stems, and impurities, rub or chop them, and sieve the ash from the cotton artemisia capillaris.
What drugs should be used with special attention?
The combined use of Chinese medicine and the combined use of Chinese and Western medicines require syndrome differentiation and treatment, and clinical individualized treatment. If you are using other drugs, please consult a doctor before taking the medicine, and inform the doctor of all your diagnosed diseases and the treatment plan you are receiving.
Instructions for use
Artemisia capillaris is slightly cold and bitter, so people with spleen and stomach deficiency should take it with caution.
What precautions should be taken when using Artemisia capillaris?
People with yellow blood accumulation and blood deficiency should use it with caution.
Avoid alcohol, oil, meat and spicy and irritating foods.
Pregnant and breastfeeding women: If you are pregnant, planning to be pregnant or are breastfeeding, please inform your doctor in time and consult whether Chinese medicine can be used for treatment.
·Children: Children must use the medicine under the guidance of a doctor and under the supervision of an adult
·Please keep the medicine properly and do not give the medicine you use to others.