Duhuo
[Medicinal] The root of Angelica pubescena Maxim.f.biserrata Shanet Yuan, a herbaceous plant of the Umbelliferae family.
[Nature and flavor and meridians] Pungent, warm, slightly bitter. Enters the liver, kidney, and bladder meridians.
[Effects] Eliminate rheumatism, dispel cold and relieve symptoms.
[Clinical application] 1. Used for rheumatic arthralgia.
Duhuo is pungent, dispersing, bitter, and dry, slightly warm and can clear the body. It has the functions of dispelling wind and dampness, relieving arthralgia and pain. It can be used for all wind-cold-damp arthralgia and joint pain, whether new or old. It is especially suitable for arthralgia in the lower body, soreness of the waist and knees, paralysis of both feet, and flexion and extension difficulties. It is often used together with mistletoe, qinjiao, and cyathula.
2. Used for wind-cold exterior symptoms with dampness.
Duhuo can dispel wind-cold-dampness and relieve symptoms, but its pungent and dispersing power is relatively slow. It is often used together with Qianghuo for wind-cold exterior symptoms with dampness.
[Prescription name] Angelica dahurica, Sichuan Angelica dahurica (wash, dry, and chop)
[General dosage and usage] One to three coins, decocted and taken.
[Comments] 1. Angelica dahurica is pungent, dispersing, bitter, dry and warm, and has the functions of dispelling wind, dispersing cold and removing dampness. It enters the liver and kidney meridians, is good at treating pain below the waist and knees, and can dispel wind and cold and relieve the symptoms. It can be used for symptoms with dampness.
2. Qianghuo and Angelica dahurica can both dispel wind, relieve the symptoms and remove dampness. The two are often used together, but Qianghuo has a good ability to relieve symptoms and is good at treating pain in the upper body. It is an important medicine for headaches; Angelica dahurica has a slow ability to relieve symptoms and is good at treating pain in the lower body. This is the difference.
[Example of prescription] Angelica dahurica, Viscum album, Gentiana macrophylla, Asarum, Saposhnikovia divaricata, Angelica sinensis, Rehmannia glutinosa, White Peony Root, Ligusticum chuanxiong, Cinnamon Bark, Poria, Ginseng, Licorice, Eucommia ulmoides, Achyranthes bidentata. Treats wind-cold-dampness arthralgia, coldness in the legs and feet, pain in the waist and knees, weakness, difficulty in bending and stretching, fear of cold and preference for heat, slow pulse and white fur.
[Literature excerpt] “Famous Doctors’ Records”: “Treats all kinds of wind, gout in all joints, no long-term new ones.”
“Tangye Bencao”: “Both are cold and damp, and the wetness cannot move or stop, and it cannot be cured without this.”
“Bencao Huiyan”: “It is a medicine that is good at moving blood, dispelling wind, dampness and cold. All symptoms of wind disease, such as the head and neck cannot bend and stretch, the waist and knees cannot bend and stretch, or the pain and difficulty in walking, numbness and uselessness, are all caused by wind and cold, and are injured by heat and dampness; it is necessary to use the bitter and pungent Duhuo to warm the qi and blood, and dispel the cold evil.”
“Bencao Qiuzhen”: “Qiang has the function of releasing the exterior, and Duhuo has the power to help the exterior. Qiang moves to the upper part of the body and If it is used upward, it can cure wandering wind headache and rheumatic joint pain. If it is used alone in the lower part of the body, it can cure latent wind headache and dampness in the feet. Although Erhuo is used to treat wind, its uses are different and must be carefully examined. ”
“Compendium of Materia Medica” says: “It has a strong smell and overflowing fragrance, so it can dredge all meridians, harmonize meridians, dredge tendons and bones, and benefit organs. If the cold and dampness are in the muscles and joints, it cannot reach the meridians and joints directly without using this strong smell. Therefore, it is an indispensable medicine for wind paralysis and paralysis.”
This product is the dried root of Anaelica pubescens Maxim.f.biserrata shan etYuan, a plant of the Umbelliferae family. It is dug when the seedlings just sprout in early spring or when the stems and leaves wither in late autumn. Remove the fibrous roots and mud and sand, bake until half dry, pile for 2~3 days, and bake until completely dry after it softens.
【Характеристики】
The root of this product is slightly cylindrical, with 2~3 branches or more at the bottom, and 10~30cm long. The root head is enlarged, conical, with many transverse wrinkles, 1.5~3cm in diameter, and the top has the remains or depressions of stems and leaves. The surface is grayish or brownish brown, with longitudinal wrinkles, transverse long lenticel-like protrusions and slightly protruding fine root marks. The texture is relatively hard and becomes soft when exposed to moisture. The cross-section of the cortex is grayish white with many scattered brown oil chambers, the wood is grayish yellow to yellow-brown, and the cambium ring is brown. It has a unique aroma and tastes bitter, pungent, and slightly numbing.
【Identification】
(1) Cross-section of this product: There are several rows of cork cells. The inner layer of the cork is narrow, with a few oil chambers. The phloem is broad, accounting for about 1/2 of the root; there are many oil chambers, arranged in several rounds, with a tangential diameter of about 153um, and surrounded by 6~10 secretory cells. The cambium is ringed. The xylem rays are 1-2 rows of cells wide; the vessels are rare, with a diameter of about 84 μm, and are often arranged radially in a single column. The thin-walled cells contain starch granules.
(2) Take 1 g of this product powder, add 10 ml of methanol, ultrasonically treat for 15 minutes, filter, and take the filtrate as the test solution. Take 1 g of the reference drug of Angelica dahurica and prepare the reference drug solution in the same way. Take the reference drug of dihydrocarbendazim angelicae and the reference drug of osthole, add methanol to prepare solutions containing 0.4 mg per 1 ml, as the reference solution. According to the thin layer chromatography method (General Rule 0502), take 8 μl of the test solution and the reference drug solution, and 4 μl of the reference solution, and spot them on the same silica gel G thin layer plate, use petroleum ether (60-90 ° C)-ethyl acetate (7:3) as the developing agent, develop, take out, dry, and inspect under ultraviolet light (365 nm). In the chromatogram of the test sample, fluorescent spots of the same color appear at the corresponding positions of the chromatograms of the reference medicinal materials and the reference substance.
[Инспекция]
The water content shall not exceed 10.0% (General Rule 0832 Method 4).
The total ash content shall not exceed 8.0% (General Rule 2302)
The acid-insoluble ash content shall not exceed 3.0% (General Rule 2302).
[Определение содержания]
Determine according to the high performance liquid chromatography method (General Rule 0512).
Chromatographic conditions and system suitability test: Octadecylsilane bonded silica gel is used as the filler; acetonitrile-water (49:51) is used as the mobile phase; the detection wavelength is 330nm. The theoretical plate number calculated according to the dihydro-angelic acid ester peak should not be less than 6000. Preparation of reference solution Take appropriate amount of osthole reference substance and dihydro-angelic acid ester reference substance, accurately weigh, and add methanol to make solutions containing 150ug and 50ug per 1m| respectively. Preparation of test solution Take about 0.5q of the powder of this product (passed through No. 3 sieve), weigh accurately, place in a stoppered conical flask, accurately add 20ml of methanol, seal, weigh, ultrasonically treat (power 250W frequency 40kHz) for 30 minutes, cool, weigh again, make up the lost weight with methanol, shake well, filter, accurately measure 5ml of the filtrate, place in a 20ml volumetric flask, add methanol to the scale, shake well, filter, take the filtrate, and get it.
Determination method Accurately aspirate 10μ1 of the two reference solution and 10~20μl of the test solution, inject into the liquid chromatograph, and determine, and get it.
Calculated on a dry basis, this product contains no less than 0.50% osthole (C15H1603) and no less than 0.080% dihydro-eugenol angelic acid ester (C1gH2005).
Кусочки отвара
[Processing]
Remove impurities, wash, moisten thoroughly, slice thinly, and dry in the sun or at low temperature.
[Характеристики]
This product is in the form of round thin slices. The outer skin is gray-brown or brown-brown with wrinkles. The cut surface of the skin is grayish white to grayish brown with many scattered brown oil spots, the wood is grayish yellow to yellowish brown, and the cambium ring is brown. It has a unique aroma. It tastes bitter, pungent, and slightly numbing.
[Инспекция]
Acid-insoluble ash is the same as the medicinal material, and shall not exceed 2.0%.
[Identification][Inspection]
(Water content, total ash)
[Определение содержания]
Same as the medicinal material.
[Properties and meridians)
Pungent, bitter, slightly warm. It enters the kidney and bladder meridians.
【Function and Indications】
Dispel wind and dampness, relieve numbness and relieve pain. Used for wind-cold-dampness arthralgia, pain in the waist and knees, headache caused by hidden wind in Shaoyin, headache caused by wind-cold and dampness.
【Usage and Dosage】
3~10g.
【Storage】
Place in a dry place to prevent mildew and moth
Where is the main origin of Angelica pubescens?
It is mainly produced in Sichuan and Hubei.
Where is the main medicinal part of Angelica pubescens?
Medicinal Part of Angelica pubescens:
This product is the dried root of Angelica pubescens Maxim.f. biserrata Shan et Yuan, a plant of the Umbelliferae family. It is dug when the seedlings just sprout in early spring or when the stems and leaves wither in late autumn, remove the fibrous roots and mud, dry it to half dry, pile it for 2~3 days, and dry it to full dry after it softens. Characteristics of the medicinal part of Angelica pubescens:
The root of this product is slightly cylindrical, with 2~3 branches or more at the bottom, and is 10~30cm long. The root head is enlarged, conical, with many transverse wrinkles, 1.5~3cm in diameter, and the top has the remains or depressions of stems and leaves. The surface is gray-brown or brown-brown, with longitudinal wrinkles, horizontal long lenticel-like protrusions and slightly protruding fine root marks.
It is hard and becomes soft when exposed to moisture. The cross-section of the cortex is grayish white with many scattered brown oil chambers, the wood is grayish yellow to yellow-brown, and the cambium ring is brown. It has a unique aroma, bitter, spicy, and slightly numbing.
How is Duhuo recorded in historical books?
“Ben Jing”: “It is used to treat wind and cold attacks, relieve pain from wounds, cure epilepsy, and hernia scars in women. Long-term use can make the body lighter and resist aging.
“Ming Yi Bie Lu”: “It can treat all kinds of thieves’ wind, and gout in all joints without long-term new ones.
“Compendium of Materia Medica”: “It is used to treat rheumatism, coldness, panting, itching of skin and muscles, cramps in hands and feet, strain, and toothache caused by wind poison.
Effects
Duhuo has the effects of dispelling wind and dampness, relieving numbness and relieving pain.
What are the main effects and clinical applications of Duhuo?
Duhuo is used for wind-cold-dampness arthralgia, pain in waist and knees, headache caused by Shaoyin hidden wind, and headache caused by wind-cold and dampness.
Arthralgia
Treats arthralgia caused by long-term deficiency of body, soreness of waist and knees, and poor flexion and extension of joints. It is used with mistletoe, Eucommia ulmoides, Codonopsis pilosula, etc.
Exterior symptoms of wind-cold and dampness
Treats aversion to cold, fever, no sweat, headache, heaviness of head, and pain all over the body caused by exogenous wind-cold and dampness. It is often used together with Notopterygium incisum.
What other effects does Duhuo have?
The commonly used medicinal diet recipes of Duhuo are as follows,
For arthralgia caused by liver and kidney deficiency and insufficient qi and blood·Duhuo, Eucommia ulmoides, Achyranthes bidentata, Paeonia lactiflora, Saposhnikovia divaricata, Rehmannia glutinosa, and Gentiana macrophylla 6g each, 2g of asarum, 1g of cinnamon bark, 10g each of tuckahoe, mistletoe, ginseng, and angelica, 3g each of chuanxiong and licorice, 1 adult rooster of the year, 50g of scallion, 20g of ginger, 6 cloves of garlic, appropriate amount of salt, and appropriate amount of cooking oil. · Grind the above herbs into fine powder, add appropriate amount of seasoning and mix well, and set aside. Kill the rooster, clean the hair, remove the internal organs, wash, and drain the water. · Put the mixed medicine and seasoning into the chicken’s belly, marinate for 30 minutes, and set aside. Put cooking oil in a heated pot, and when it is 70% hot, fry the chicken in the oil. When the chicken turns yellow and is cooked, remove it from the oil and drain it for later use.
Heat another pot and add a little cooked oil, stir-fry ginger and scallion, add clear soup, adjust the taste, and cook the fried chicken in the soup for a while, and wait until the soup boils. Serve with meals. It is suitable for long-term obstruction of wind, cold, and dampness, liver and kidney Deficiency of both qi and blood, resulting in back pain, leg pain, weakness, poor flexion and extension, pale complexion, etc. It can be used as an auxiliary treatment for chronic arthritis, sciatica, etc., which are rheumatic and qi and blood deficiency.
Note: The use of Chinese herbal medicines must be differentiated and treated, and should be used under the guidance of professional Chinese medicine practitioners. They should not be used at will, and should not be used at will, let alone listen to Chinese medicine prescriptions and advertisements.
What are the compound preparations containing Duhuo?
Duhuo Jisheng Pills
Nourishes blood and relaxes muscles, dispels wind and dampness, and nourishes the liver and kidneys. It is used for arthritis caused by wind, cold and dampness, liver and kidney deficiency, and qi and blood deficiency, with symptoms of cold pain in the waist and knees and poor flexion and extension.
Duhuo Jisheng Decoction
Dispels rheumatism, stops arthralgia, benefits the liver and kidneys, and replenishes qi and blood. It is mainly used to treat long-term arthralgia, liver and kidney deficiency, and qi and blood deficiency. Pain in the waist and knees, weakness, poor flexion and extension of the limbs, or numbness, fear of cold and preference for warmth, heart Palpitations and shortness of breath, pale tongue with white fur, and weak pulse.
Qianghuo Shengshi Decoction
Dispels wind, dampness, and relieves pain. It is mainly used to treat rheumatism in the surface. Shoulder and back pain cannot be looked back, headache and heaviness, or waist and spine pain, difficult to turn.
Duhuo Xixin Decoction
Mainly treats exogenous headache, evil in Shaoyin, headache and pain in the cheek,
Modern research progress on Duhuo
This product has multiple pharmacological effects such as anti-inflammatory, analgesic, sedative, antiarrhythmic, platelet aggregation inhibition, spasmolysis, antithrombotic, anti-tumor and anti-aging.
Usage method
Duhuo has the effect of dispelling wind and dampness, clearing numbness and relieving pain. Generally, Duhuo decoction pieces are used, both for internal and external use. Please follow the doctor’s advice for specific medication.
How to use Duhuo correctly?
When Duhuo decoction is taken orally, the usual dosage is 3~10g.
When used externally, take an appropriate amount of Duhuo, decoct the decoction to wash the affected area to treat skin itching.
Duhuo is usually used in decoctions, decocted and taken, or soaked in wine, made into powder or pills. However, the use of Chinese herbal medicines must be based on syndrome differentiation and treatment, and should be used under the guidance of professional Chinese medicine practitioners. They should not be used at will, and should not be used at will, let alone listen to Chinese medicine prescriptions and advertisements.
Common Chinese medicine combinations are as follows:
Duhuo with Qianghuo: Duhuo can dispel rheumatism, relieve pain, and release the exterior. It is good at dispersing internal wind and cold dampness, and treats wind-cold dampness arthralgia below the waist; Qianghuo can dispel cold and dispel wind, overcome dampness and relieve pain, and release the exterior. It is good at dispersing wind and cold dampness on the surface of the muscles, and treats wind-cold dampness arthralgia in the upper body. The two medicines are matched, go from the inside to the surface, dispersing wind, cold and dampness, and relieving pain. They can treat rheumatic arthralgia pain in both the upper and lower parts.
In addition, Duhuo can also be soaked in wine. It can be soaked in wine with Chinese medicines such as Achyranthes bidentata and cinnamon, which has the effects of removing dampness and relieving pain, warming the meridians and activating blood circulation.
How to prepare Duhuo?
Take the original medicinal materials, remove impurities and those that are oily and black, separate the big and small ones, wash them with water, moisten them thoroughly, cut them into thin slices, and dry them in the sun or at low temperature. Sieve out the debris.
Which drugs should be used with Duhuo at the same time with special attention?
The combined use of Chinese medicine and the combined use of Chinese and Western medicine requires syndrome differentiation and clinical individualized treatment. If you are using other drugs, please consult a doctor before taking the medicine, and inform the doctor of all your diagnosed diseases and the treatment plan you are receiving.
Instructions for use
Duhuo is pungent, warm, bitter and dry, and it is easy to hurt qi and consume blood. Therefore, those with yin deficiency and blood dryness or qi and blood deficiency, as well as those without wind, cold and dampness, should be cautious when taking it, and those with liver wind should not take it.
What precautions should be taken when using Duhuo?
·The internal dosage should not be too large, and those with yin deficiency and blood dryness should be cautious when taking it.
·This product has a unique aroma, bitter and pungent taste, and slightly numb tongue. It is better to use thick and fat roots with strong aroma. Use it raw.
·During medication, be careful not to eat cold, raw and cold food, spicy and greasy food.
Pregnant and lactating women: If you are pregnant, planning to get pregnant or are lactating, please inform your doctor in time and consult whether Chinese medicine can be used for treatment.
· Children: Children should take medicine under the guidance of a doctor and adult supervision
· Please properly store the medicinal materials and do not give your own medicinal materials to others.
How to identify and use Duhuo?
Duhuo and Qianghuo
Qianghuo is a herbal medicine for relieving exterior symptoms. It is the rhizome and root of Notopterygium incisum Ting ex H.T.Chang or Notopterygium forbesii Boiss. of the Umbelliferae family.
Duhuo is a herbal medicine for rheumatism. It is the dried root of Angelica pubescens Maxim.f. biserrata Shan et Yuan of the Umbelliferae family.
Both can dispel rheumatism, relieve pain, and relieve the symptoms of wind-cold dampness, wind-cold dampness and superficial symptoms, and headaches. However, Qianghuo is more dry and has a strong dispersing power, and is often used for wind-cold dampness and pain in the upper body; Duhuo is more mild and has a weaker dispersing power, and is often used for wind-cold dampness and pain in the lower body. If there is wind-cold dampness and pain all over the body, the two are often used in combination.
Medication Tips
The most frequently asked questions by patients
The efficacy and effects of Duhuo Jisheng Pills
Duhuo Jisheng Pills are a tonic and dampness-removing agent, composed of Duhuo, mistletoe, Rehmannia glutinosa, Achyranthes bidentata, Asarum, Gentiana macrophylla, Poria, Cinnamon bark, Saposhnikovia divaricata, Chuanxiong, Codonopsis pilosula, Licorice and Angelica sinensis (made with wine), White Peony Root, and Eucommia ulmoides (made with salt water). It has the effects of nourishing blood and relaxing muscles, dispelling wind and dampness. It is used for wind-cold dampness and pain in the waist and knees, and poor flexion and extension.
Efficacy and effects of Compound Duhuo Indomethacin Capsules
Compound Duhuo Indomethacin Capsules are Western medicines, and their ingredients include Duhuo, Qianghuo, papaya, Achyranthes bidentata, indomethacin, and piroxicam.
It is used for rheumatoid arthritis, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and various acute musculoskeletal diseases.
Oral administration. 1 capsule at a time, 2 times a day. Take after meals, double the dose for the first time. The maximum daily dose of piroxicam is no more than 20mg.
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