桂枝茯苓丸-Gui Zhi Fu Ling Wan,Guizhi Fuling Pills
Chinese Pharmacopoeia: Guizhi Fuling Pills
Prescription Guizhi 100g Fuling 100g Peony Bark 100g Red Peony Root 100g Peach Kernel 100g
Properties Brown honey pills; sweet.
Processing Grind the above five ingredients into fine powder, sieve and mix well. Add 90-110g refined honey to every 100g powder to make large honey pills.
Functions and Indications Activate blood circulation, dissolve blood stasis and eliminate symptoms. Used for women with lumps, blood stasis, amenorrhea, abdominal pain during menstruation, and postpartum lochia.
Usage and Dosage Oral, 1 pill at a time, 1-2 times a day.
Note Pregnant women should use with caution.
Specifications Each pill weighs 6g
Storage Sealed.
Extract from the Chinese Pharmacopoeia
Volume 2 of the Golden Chamber: Guizhi Fuling Pills
Other names: Duoming Pills (Volume 12 of the Complete Prescriptions for Women), Mudan Pills (Volume 357 of the Puji Prescriptions), Duoming Pills (Volume 12 of the Annotated Prescriptions for Women), Guixin Fuling Pills (Volume 15 of the Zhang’s Medical Guide).
Prescription: Guizhi, Fuling, Mudan (core removed), peach kernel (peeled, tip removed, boiled), and Shaoyao (equal parts).
Preparation: Grind the five ingredients above into powder, and make pills with refined honey, the size of rabbit feces.
Pharmacological effects: Effects on blood rheology. Chinese Patent Medicine Research, 1986 (5): 24-26. Experiments show that intravenous or oral administration of this prescription can significantly reduce whole blood specific viscosity, whole blood reduced specific viscosity, plasma specific viscosity, fibrinogen concentration, and increase red blood cell electrophoresis speed. Experiments have found that this drug is effective in both intravenous and oral administration, with the former having a fast effect and the latter having a long-lasting effect. And oral administration has a particularly strong effect in reducing plasma viscosity.
Functions and indications: Activate blood circulation and dissipate blood stasis, and slowly dissipate lumps. Treat women with chronic symptom diseases, menstruation has not been stopped for three months, and there is continuous bleeding, fetal movement above the navel; difficult menstruation; abdominal distension and pain after menstruation; dystocia; fetal death in the abdomen; retained placenta; postpartum lochia that is not completely discharged and abdominal pain that refuses to be pressed.
Usage and dosage: Take 1 pill on an empty stomach each time, if you don’t know, increase to 3 pills.
Remarks: In the formula, cinnamon twig warms the yang and dredges the meridians, peony nourishes blood and harmonizes the camp, peach kernel breaks blood and eliminates symptoms, moutan bark activates blood circulation and dissipates blood stasis, and poria invigorates qi and nourishes the heart. Make pills with honey to take the meaning of gradual dissipation.
Excerpt from “Golden Chamber Synopsis” Volume 2
Yan Gengfu Prescription: Guizhi Fuling Pills
Prescription: 15g cinnamon twig, 15g poria, 15g peach kernel (peeled and pointed), 15g moutan bark, 15g peony.
Functions and indications: Promote blood circulation and dissipate blood stasis, dissipate lumps and resolve knots. It is used to treat stasis in the uterus, which is a problem.
Usage and dosage: Grind into fine powder, make pills with refined honey, and take 10 grams every morning and evening before meals.
Excerpt: Yan Gengfu’s prescription
Volume 2 of the Golden Chamber: Guizhi Fuling Pills
Other names: Duoming Pills, Mudan Pills, Duoming Pills, Xianchuan Baoming Pills, Anjie Pills
Prescription: Guizhi, Fuling, Mudan (without the core), peach kernel (without the skin and tip, boiled), and Shaoyao, each in equal parts.
Preparation method: Grind the above into powder, make pills with refined honey, as big as rabbit feces.
Functions and indications: Eliminate symptoms. Dissipate blood stasis and generate new blood, and harmonize qi and blood. It is used for women with chronic diseases, who have stopped menstruating for less than 3 months, and have continuous bleeding, and fetal movement above the navel, which is a chronic disease. Women have miscarriages, heavy bleeding, and the fetus dies in the womb. They hate cold, their fingers, lips, mouth, nails are blue and white, their faces are yellow and black, or the fetus is on the heart, they are suffocated and want to die, cold sweats come out, they are short of breath and cannot eat, or they eat poison, or take herbal medicine by mistake, which hurts the fetus and moves the qi.
Clinical application ① Syndrome (ectopic pregnancy) “Shandong Medical Journal” (1966; 3: 15): Mi Moumou, female, 25 years old. She has been married for 8 years without giving birth, and had a miscarriage four years ago. This time, the menstruation has not come for two months. In the past two days, the lower abdomen suddenly hurts and falls, and the vagina drips blood, the blood is purple and black. The face is yellow and thin, the voice is low, the spirit is weak, the appearance is acute, the pain in the lower abdomen refuses to be pressed, the tongue is white, and the pulse is deep and slippery. Western medicine gynecological examination: the uterus is enlarged like a chicken egg, the posterior fornix is full and tender, and it feels like a cyst. There is a fist-sized mass behind the uterus and the right appendage, and the tenderness is obvious. Western medicine diagnosis: ectopic pregnancy. TCM diagnosis: blood stasis. The patient refused surgery, so Chinese medicine and Guizhi Fuling Wan were used for 3 times. On the second day, the abdominal pain was relieved, the vaginal bleeding became light red blood, the amount increased, the appetite increased, and the spirit improved; after taking it for 3 days, a flat round blood clot flowed out, light red, like rotten meat, and continued to bleed black purple blood, the amount decreased, the abdominal pain disappeared, (but there was still tenderness), and the pulse was slow; after taking it for another 3 days, the bleeding stopped and the abdominal tenderness disappeared. The posterior fornix was slightly full, without tenderness, the uterus was in the middle, and the appendages were double (one). After taking the medicine for another 2 days, the blood turned bright red and the amount was large; changed to taking Jiajian Jiaoai Decoction for 2 doses, the bleeding stopped, and all symptoms disappeared. After continuing to observe for 1 month, the patient was in good health, and menstruation came once, lasting 4 days. ② Postpartum lochia is not clean “Pu Fuzhou’s Medical Case”: Chen Moumou, female, adult, married. First visit on May 7, 1963: Since giving birth at the end of March this year, the lochia has not been cleared, the amount is not much, the color is light red, sometimes there are small purple blood clots, and the back pain has been since the birth, the whole body is painful when pressing, especially the lower body, sometimes the left lower abdomen is painful, there is varicose veins from the left waist to the upper 1/3 of the thigh, the appetite is poor, the stool is loose, the urine is yellow, the sleep is OK, the complexion is dull, the pulse is strong above and weak below, the right Guan string is slow, the left Guan string is large, the inch and the foot are heavy and astringent, the tongue is light red and has no coating, due to improper postpartum conditioning, resulting in disharmony between the Ying and Wei, disorder of Qi and blood, and unresolved lochia. The treatment should be to regulate the Ying and Wei, and harmonize the blood and eliminate blood stasis. Prescription: 1.5 qian of cinnamon twig, 2 qian of white peony root, 3 qian of Poria, 1 qian of stir-fried moutan bark, 1 qian of peach kernel (peeled), 8 fen of roasted ginger, 4 jujubes, take 5 doses. Follow-up on the 16th: After taking the medicine, the lochia has been exhausted, the pain in the lower abdomen and waist and legs has disappeared, the appetite has improved, the bowel movements are normal, the pulse is deep, stringy, and weak, and the tongue is pale and not bitter. The stagnation has disappeared, and it is appropriate to replenish both qi and blood. 40 pills of Shiquan Dabu Pills, 1 pill each morning and evening, have returned to normal after taking it. ③ Pelvic inflammatory disease “New Chinese Medicine” (1975; 6: 40): Guizhi Fuling Decoction was used to treat 50 cases of pelvic inflammatory disease, including 35 cases of chronic pelvic inflammatory disease, 27 cases were cured, and the efficacy reached 77.1%. The average time for pain symptoms to disappear was 16.4 days, the average time for adnexal tenderness to be relieved was 18 days, and the average time for adnexal tenderness to disappear was 18.9 days. 10 cases of subacute pelvic inflammatory disease, 8 cases were cured, the average time for pain symptoms to disappear was 6.8 days, and the average time for adnexal tenderness to be relieved was 11.1 days. 5 cases of acute pelvic inflammatory disease, 4 cases were cured, and various antibiotics were used in combination in the acute stage. The remaining cases were ineffective.
Dosage and administration: Duoming Pill (Volume 12 of “Good Prescriptions for Women”), Mudan Pill, Duoming Pill (Volume 357 of “Puji Prescriptions”), Xianchuan Baoming Pill, Anjie Pill (Volume 2 of “The Heart Method of Pregnancy and Childbirth”). The name of this prescription is quoted as “Guixin Fuling Pill” in “Zhang’s Medical Encyclopedia”.
Comments by various scholars ① “Two Notes on the Golden Chamber and Jade Box”: Cinnamon twig, peach kernel, moutan bark, and peony can remove bad blood; Poria can also benefit the blood between the waist and navel, that is, breaking blood. However, there are those that disperse and slow down, those that collect and penetrate, and those that gather can be dispersed with the pungent taste of cinnamon twig; the liver stores blood, and those with blood accumulation are anxious in the liver, so they can be relieved with the sweet taste of peach kernel and moutan bark; those with yin qi being activated can be collected with the sour taste of peony; after the bad blood is broken, it can be supplemented with the mild penetrating taste of Poria and other herbs to facilitate its movement. ② “The Meaning of the Golden Chamber”: This prescription is a slow-acting agent for removing blood stasis and eliminating symptoms. In the prescription, peach kernel and moutan bark are used to promote blood circulation and dissipate blood stasis; an equal amount of white peony root is used to nourish and regulate blood, so as to remove blood stasis and promote new blood; adding cinnamon twig can not only warm and circulate blood vessels to assist peach kernel, but also obtain white peony root to harmonize qi and blood; with the mild penetrating and damp-removing effect of Poria cocos, it has the function of removing dampness and stopping blood. The whole prescription is a remedy for removing blood stasis, promoting new blood, and harmonizing qi and blood. To make honey pills, the method of use is to start with a small amount, and gradually increase the amount, which also means that the symptoms will be relieved without hurting the fetus, and it also shows that people should be cautious about pregnancy diseases. In this way, the symptoms will be eliminated and the blood will be stopped, and the fetus will be safe. Therefore, this prescription is a good prescription for treating pregnancy diseases and blood stasis and fetal injury.
Excerpt from Volume 2 of “Golden Chamber”
Han Dynasty “Golden Chamber Essentials”: Guizhi Fuling Pill
Composition: cinnamon twig, Poria cocos, moutan bark, peach kernel, peony root.
Usage: Take equal parts of the above medicines, grind them into fine powder, and make pills with refined honey. Take 6-9 grams each time, 1-3 times a day, before meals.
Efficacy: Activate blood circulation, dissipate blood stasis, and eliminate symptoms.
Indications: Indications: Women with lumps, or amenorrhea due to blood stasis, abdominal pain during menstruation, postpartum lochia, pale purple tongue, white fur, stringy and fine pulse.
Clinical application: It is mainly used in the treatment of salpingitis, polycystic ovary syndrome, uterine fibroids, metrorrhagia, hematospermia, atrial fibrillation and other diseases.
1. Salpingitis: Guizhi Fuling Wan was used to treat 50 patients with salpingitis. One course of treatment was 14 days, and 1-2 courses of treatment were given depending on the patient’s condition. Clinical manifestations were used as the efficacy evaluation index. Results: 18 cases, 18 cases were markedly effective, 7 cases were effective, and 7 cases were ineffective, with a total effective rate of 86%. (Chinese Journal of Experimental Traditional Chinese Medicine, 2011, No. 6)
2. Polycystic ovary syndrome: This prescription plus conventional western medicine was used to treat 50 patients with polycystic ovary syndrome, and the patients were randomly compared with 50 patients treated with conventional western medicine alone. The course of treatment was 3 months. The clinical manifestations were used as the efficacy evaluation index. Results: The total effective rate of the treatment group was 84%, and the total effective rate of the control group was 42%. The difference between the two groups was statistically significant. (Shandong Medicine, 2006, No. 1)
3. Uterine fibroids: Guizhi Fuling Pill plus conventional western medicine was used to treat 62 patients with uterine fibroids, and the patients were randomly compared with 50 patients treated with conventional western medicine alone. The course of treatment was 3 months. The clinical manifestations were used as the efficacy evaluation index. Results: Most of the patients were treated for 18 menstrual cycles, 25 were cured, 21 were significantly effective, 12 were effective, 4 were ineffective, and the total effective rate was 93.55%. (Sichuan Traditional Chinese Medicine, 2006, No. 1)
4. Menorrhagia: This prescription with added ingredients was used to treat 136 patients with type 2 metrorrhagia, and clinical manifestations were used as the efficacy evaluation index. Results: 123 cases were cured, 9 cases were effective, and 4 cases were ineffective, with a total effective rate of 97.06%. (Journal of Traditional Chinese Medicine, 2008, No. 4)
5. Hemospermia: This prescription with added ingredients was used to treat 33 patients with refractory hemospermia, and 31 cases were randomly compared with Western medicine (oral moxifloxacin hydrochloride tablets), with 5 days as one course of treatment and a maximum of 3 courses of treatment. Clinical manifestations were used as the efficacy evaluation index. Results: The total effective rate of the treatment group was 90.9%, and the total effective rate of the control group was 35.5%; the long and short diameters of the seminal vesicles in the treatment group were significantly reduced after treatment compared with those before treatment (P<0.01); there was also a significant difference compared with the control group after treatment (P<0.01). (Chinese Materia Medica, 2012, No. 12)
6. Atrial fibrillation: Guizhi Fuling Wan was used to treat 41 patients with non-valvular atrial fibrillation, and 40 patients were randomly compared with Western medicine (oral warfarin sodium). Results: After treatment, the incidence of thrombosis in the observation group and the control group was 7.59% and 7.31%, respectively, with no significant difference (P>0.05); the incidence of bleeding in the observation group and the control group was 2.5% and 8.76%, respectively, with a significant difference between the two groups (P<0.05). The observation group had scattered ecchymoses on the skin and mucous membranes, and bleeding in the gums and conjunctiva, while the control group had severe gastrointestinal bleeding. (Journal of Traditional Chinese Medicine, No. 1, 2009)
Explanation of the prescription: In this prescription, cinnamon twig warms and dredges the meridians and removes stasis; Poria strengthens the spleen and nourishes the heart and removes dampness; Peony bark disperses blood and removes stasis and heat; Peony softens the liver, regulates the spleen and regulates qi and blood; Peach kernel promotes blood circulation and removes stasis and breaks up blood clots; Peony and cinnamon twig are one yin and one yang, Poria and Peony bark are one qi and one blood, and Peach kernel can both break and disperse, and together they have the effects of promoting blood circulation and removing stasis and regulating qi and blood.
Guizhi Fuling Pills are widely used in clinical practice and can also treat prostatitis, chronic pelvic inflammatory disease, ovarian cysts, ovarian malignant tumors, breast hyperplasia, prostatic hyperplasia, prostatitis, epididymitis, retinal vein occlusion, pregnancy-induced hypertension, angina pectoris, hyperlipidemia, infertility, chronic renal insufficiency and other diseases.
Modern research Modern pharmacological research has confirmed that the blood-activating and blood-stasis-removing drugs in the prescription can improve tissue microcirculation, dilate blood vessels, improve blood oxygen supply around the lesion and induce ovulation, promote endometrial shedding, remove intrauterine blood stasis, promote the discharge of residual embryonic tissue, and improve the function of uterine muscle contraction.
Prescription Song Jinkui Guizhi Fuling Wan, peach kernel, peony and peony, equal parts of powder and honey pills, slowly dissipate the symptoms and lumps, and the fetus can be safe.
Excerpt from Han Dynasty “Jinkui Yaolue”
Guizhi Fuling Wan, [guizhifulingwan], Chinese patent medicine
Effects and efficacy
Guizhi Fuling Wan is a Chinese medicine preparation that activates blood circulation, dissipates blood stasis and eliminates lumps. It is mainly used for women with lumps or blood stasis amenorrhea, abdominal pain during menstruation, and postpartum lochia.
The prescription is explained as follows
The cinnamon twig in the prescription is pungent and sweet, warm in nature, warms the meridians, removes stagnation and removes blood stasis, and is the main drug. Peach kernel tastes bitter, good at relieving blood stasis, breaking up bad blood, and eliminating scars: Peony bark tastes slightly bitter, slightly cold in nature, can disperse blood and remove blood stasis, cool blood and clear heat; Red peony root tastes bitter and sour, slightly cold in nature, harmonizes blood and nourishes blood, makes it disappear without hurting the body, and is a ministerial medicine. Poria strengthens the spleen and penetrates dampness, and is used as a source of transformation, as an adjuvant. All medicines are used together to play the role of promoting blood circulation, removing blood stasis, and eliminating.
What diseases can Guizhi Fuling Wan be used to treat?
This product has the effects of promoting blood circulation, removing blood stasis, and eliminating symptoms. It is used to treat endometritis, adnexitis, irregular menstruation, dysmenorrhea, vaginal bleeding after abortion, uterine fibroids, ectopic pregnancy, ovarian tumors, and infertility.
What symptoms can Guizhi Fuling Wan be used to relieve?
This product can be used to relieve symptoms such as irregular menstruation, amenorrhea, and dysmenorrhea.
What other uses does Guizhi Fuling Wan have?
It can also be used for patients with prostate hypertrophy, goiter, hepatosplenomegaly and other syndromes that are due to blood stasis and dampness
Меры предосторожности
If you are using other medicines, please consult a doctor or pharmacist before using this product.
Avoid cold, spicy and greasy food during medication.
Who is strictly prohibited from using Guizhi Fuling Wan?
People who are allergic to this product and other ingredients are prohibited.
Pregnant women are prohibited.
Who needs to use Guizhi Fuling Wan with caution?
People with allergic constitutions should use it with caution.
People with symptoms and continuous leakage after pregnancy should follow the doctor’s advice and use it with caution.
People with weak bodies and heavy vaginal bleeding should not use it.
Women during menstruation should stop taking it.
Can special groups use Guizhi Fuling Wan?
Pregnant and lactating women: Pregnant women are prohibited. If you are pregnant, planning to become pregnant or are lactating, you should inform your doctor in time and consult to choose the best treatment plan.
. Children: Children should use the medicine under the guidance of a doctor and under the supervision of an adult.
·Others: People with weak constitution and excessive vaginal bleeding should not use it.
Which drugs will Guizhi Fuling Pill interact with?
This product contains red peony root and should not be used with drugs containing Veratrum.
This product may interact with other drugs when used at the same time. Therefore, if you have a confirmed disease or are undergoing treatment, please consult a doctor or pharmacist.
Dosage and Administration
Please take it according to the dosage and administration. For children, the elderly, and breastfeeding women, please consult a doctor for specific medication. Do not take medication at will.
What dosage forms or specifications does Guizhi Fuling Pill have?
Large honey pill: each pill weighs 6g.
The above content is referenced from the 2020 edition of the “Chinese Pharmacopoeia” and the “Clinical Drug Use Instructions of the People’s Republic of China-Chinese Medicine Formula Preparation Volume (2015 Edition)”. Guizhi Fuling Pills produced by different manufacturers also have other dosage forms and specifications, such as vegetarian pills (large pills), each 10 pills weigh 2.2g; vegetarian pills (small pills), each 10 pills weigh 1.5g; honey pills, each 100 pills weigh 10g, etc.
What is the specific use of Guizhi Fuling Wan?
According to the dosage form of the 2020 edition of the Chinese Pharmacopoeia: oral. 1 pill at a time, 1-2 times a day. For the specific use of other dosage forms and specifications of drugs, please refer to the instructions or follow the doctor’s advice.
This medicine should be taken after meals and stopped during menstruation. 3 months is a course of treatment, or follow the doctor’s advice.
If you find that the contents of the drug instructions are inconsistent before taking the medicine, please consult a doctor or pharmacist in time.
Instructions for use
This product is prohibited when the properties change. Please keep this product out of reach of children.
If the symptoms do not improve after taking the medicine for three days, you should go to the hospital for treatment.
What should I do if I miss Guizhi Fuling Wan?
If the missed medication time is short, please make up as soon as possible, but if it is almost time for the next medication (more than half of the interval between two normal medications), please skip the missed dose and take the medicine directly at the next medication time.
Remember not to take two doses at a time to avoid toxic reactions.
·If you are not sure of the dosage, please consult a doctor or pharmacist.
Use Guizhi FulingWhat should I do if I overdose on the pills?
· If the dosage exceeds the dosage specified in the drug instructions by more than one times, or exceeds the dosage prescribed by the doctor, it is an overdose. When taking an overdose of the drug, if there is no discomfort, it is recommended to continue to observe and stop taking the drug once next time; if there is discomfort, and it is still not relieved after stopping the drug, you should go to the hospital for treatment.
What are the adverse reactions of Guizhi Fuling Pills?
Occasionally, stomach discomfort and dull pain are seen after taking the medicine, which generally disappear on their own after stopping the medicine.
Under what circumstances should I stop using Guizhi Fuling Pills immediately?
If stomach discomfort and dull pain occur after taking the medicine, the medicine should be stopped for observation.
In addition, you may have other side effects. If you feel uncomfortable after taking the medicine, please inform the doctor in time. The doctor will judge whether to stop the medicine or take necessary measures according to the severity of the adverse reaction.
Under what circumstances do you need to go to the hospital as soon as possible?
If the symptoms do not improve after taking the medicine for three days, or if the stomach pain worsens, you should go to the hospital for treatment. In addition, if other adverse reactions occur during medication, please consult a doctor in time.
Medication Tips
The most frequently asked questions by patients
Can Guizhi Fuling Pills be taken for a long time?
This product cannot be taken for a long time. Long-term use of Guizhi Fuling Pills may have some adverse effects on the stomach. The specific course of medication should be determined by the doctor according to the needs of the condition. Do not take it for a long time on your own to avoid delaying treatment or aggravating the condition. If it is effective, stop using it as soon as the disease is cured. If it is ineffective, consider using other drugs. Please consult a doctor for details.
What should I pay attention to in my diet during medication?
During medication, the diet should be light, and avoid raw, cold, spicy, and greasy foods.
Отзывы
Отзывов пока нет.